Displaying 1 of 1 2011 Format: Book Author: Stockwell, Brent R., author. Title: The quest for the cure : the science and stories behind the next generation of medicines / Brent R. Stockwell. Publisher, Date: New York : Columbia University Press, [2011], ©2011. New York : Columbia University Press, ©2011. Description: xviii, 265 pages : illustrations ; 22 cm Summary: A leading researcher in chemical biology offers a behind-the-scenes tour of today's medical innovations, tracing key 20th-century pharmacological milestones while profiling sophisticated, emerging approaches to drug design that may enable breakthrough treatments for seemingly incurable diseases. Subjects: Drug development. Drugs -- Design. Proteins -- Metabolism. Notes: Includes bibliographical references (pages 229-249) and index. Contents: The drug discovery crisis -- A new science of molecules -- The birth of the first cancer drugs -- A new company creating drug cocktails -- The undruggable RAS protein -- The druggable genome -- Peering inside proteins -- The nature of interactions between proteins -- Blocking protein-protein interactions -- A revolution in peptide synthesis -- A vast array of drug candidates -- Moving outside the small molecule box -- Accelerating the arrival of next generation drugs. LCCN: 2010053573 ISBN: 9780231152129 0231152124 Other Number: 694223942 System Availability: 1 Current Holds: 0 # Local items: 1 Control Number: 290415 # Local items in: 0 # System items in: 0 Call Number: 615.19 Stockwel Place Hold Add to My List Expand All | Collapse All Availability Map It Suggestions and more Displaying 1 of 1
